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KMID : 0383819730200040010
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Tuberculosis and Respiratory Diseases
1973 Volume.20 No. 4 p.10 ~ p.12
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Experience of Temporary Positive Conversion after Several Months of Negative Sputum for Tubercle Bacilli by Chemotherapy in Pulmonary Tuterculosis Patients.
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홍영표(洪永杓)/Young Pyo Hong
송호성(宋浩星)/Ho Sung Song
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Abstract
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Among 512 pulmonary tuberculosis patients treated by anti-tuberculosis drugs and
who knave had more than six months of negative sputum for tubercle bacilli, 45
Patients have experienced temporary sputum positive conversion after more than three
months of consecutive negative sputum. Clinical, bacteriological, and roentgenological
findings of these patients were compared with those of sixteen reactivated patients.
Temporary positive conversion have continued for one to two months in 41 patients and
three months in remaining two patients. It should be regarded as temporary positive
conversion if the first positive converted sputum was smear positive but no growth
occur on culture.
There were two cases of Mitchision's transitional resistance in temporary positive
converted patients before first negative conversion, and three before second negative
conversion. And nine cases of drug resistance have developed before first negative
conversion and all by second positive conversion in reactivated patients.
Roentgenologically, no or minimal temporary changes were observed in temporarily
positive converted patients and significant changes were shown in sirs of reactivated
cases. 45 temporarily converted cases and three reactivated cases showed no or
negligible symptoms, and significant clinical symptoms and signs were met in three
temporarily converted and thirteen reactivated cases.
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